Despite using a powerful healing technique, Kabuto's wounds are too extensive for him to deal with. When Naruto collapses due to the severity of Kabuto's last attack, a strike to Naruto's heart, Tsunade does what she can, determined to save him and his dream of becoming hokage. Her efforts work, and he regains consciousness long enough to claim the necklace he has won in the bet. Orochimaru, recognizing Naruto as a potential future threat, tries to kill him. Tsunade, determined to make sure Naruto becomes Hokage, overcomes her fear of blood and uses herself as a human shield to block the attack. When asked why she would risk her life to save him, Tsunade replies that it is her duty as the Fifth Hokage, finally accepting the role she was offered. Intending to eliminate his former teammates, Orochimaru summons Manda while Tsunade and Jiraiya summon Katsuyu and Gamabunta respectively.
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